Midlife & Metabolic Health
Hormone Therapy
How estrogen and testosterone support the brain and body, why they change in perimenopause and menopause, and how hormone therapy can help.

What is it?
Estrogen and testosterone do far more than regulate reproduction. Estrogen receptors are found throughout the body, including the brain, bones, heart and blood vessels, skin, bladder and vaginal tissue. That is why falling estrogen can affect sleep, mood, memory, concentration, body temperature and bone density, not only periods.
Testosterone matters for women too. It is present in smaller amounts than in men, and it plays a part in energy, muscle and sexual desire.
Why these hormones are needed in perimenopause and menopause
During perimenopause, hormone levels swing unpredictably before they fall. After menopause, estrogen and progesterone stay low, and testosterone declines gradually with age. Those shifts explain many of the symptoms women describe in midlife, and they also affect long-term bone and heart health.
The role of hormone therapy
Hormone therapy replaces some of what the body is no longer producing. For many women it is the most effective way to relieve hot flashes, night sweats and poor sleep, and it can help protect bone density. It is not right for everyone, and it is never one-size-fits-all.
What symptoms or concerns might bring you to us?
Hot flashes and night sweats
Poor sleep, low mood or anxiety that feels new
Brain fog, forgetfulness or difficulty concentrating
Low energy or reduced sex drive
Vaginal dryness or discomfort
Concerns about bone health or a family history of osteoporosis
How Plaza approaches it
We start with your symptoms, your history and your goals, then review the benefits and risks that apply to you specifically, including your personal and family history of breast cancer, blood clots, stroke and heart disease.
Once you begin, we follow up, adjust and reassess over time. Hormone therapy is an ongoing conversation, not a single decision.
Treatment options
Estrogen therapy as a pill, patch, gel or spray
Progesterone for women who still have a uterus
Testosterone therapy where appropriate
Bioidentical hormone options
Hormone pellet therapy
Local vaginal estrogen for genitourinary symptoms
Non-hormonal options for women who cannot or prefer not to use hormones
Why choose Plaza
Hormone therapy works best when it is prescribed by people who know your history and will still be seeing you next year. Every plan is individualized, and we never assume one approach is right for every woman.
[Placeholder: a real review about hormone therapy at Plaza.]
[Patient name], Plaza patient
Plaza Menopause Care
Midlife changes often overlap with this. We can look at the whole picture.
Related services
Midlife & Metabolic Health
Hormone Therapy
How estrogen and testosterone support the brain and body, why they change in perimenopause and menopause, and how hormone therapy can help.
Midlife & Metabolic Health
Hormone Therapy
How estrogen and testosterone support the brain and body, why they change in perimenopause and menopause, and how hormone therapy can help.

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